GIST Risk Tables*

Modified NIH criteria
Tumor site Size (cm) Mitotic count (per 50 HPFs) Proportion of operable GISTs* (%) 10-year recurrence-free survival* (%)
Very low risk Any <2.0 ≤5 12 95
Low risk Any 2.1-5.0 ≤5 29 90
Intermediate risk Gastric ≤5 6-10 14 87
Intermediate risk Gastric 5.1-10.0 ≤5 14 87
High risk Any >10.0 Any 46 36
High risk Any Any >10 46 36
High risk Any >5 >5 46 36
High risk Not gastric ≤5 >5 46 36
High risk Not gastric 5.1-10.0 ≤5 46 36
AFIP criteria
Size (cm) Mitotic count Proportion of operable GISTs* (%) 10-year recurrence-free survival* (%)
Group 1 <2.0 ≤5 13 95
Group 2 2.1-5.0 ≤5 29 90
Group 3a 5.1-10 ≤5 19 80
Group 3b >10 ≤5 9 62
Group 4 <2 >5 0.5 46
Group 5 2.1-5.0 >5 8 49
Group 6a 5.1-10 >5 12 25
Group 6b >10 >5 10 9
  1. * Joensuu H, Vehtari A, Riihimäki J, et al. Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts. Lancet Oncology 2012; 13: 265–74, Joensuu H, Hohenberger P, Corless CL. Gastrointestinal stromal tumour. The Lancet 2013; 382, 973–83